rs7300972
A SNP in the SELPLG gene on chromosome 12. Its most notable genotype is T;T: common in complete genomics
- Gene
- SELPLG
- Location
- Chr 12108,623,488 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, FamilyTreeDNA
- Minor allele frequency
- 8%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 10 HapMap populations.
- AverageT;T 79%
- European ancestry (Utah)T;T 92%
- Han Chinese (Beijing)T;T 100%
- Japanese (Tokyo)T;T 100%
- Yoruba (Nigeria)T;T 47%
- African ancestry (Southwest US)T;T 48%
- Gujarati IndianT;T 89%
- Luhya (Kenya)T;T 53%
- Mexican ancestry (Los Angeles)T;T 95%
- Maasai (Kenya)T;T 72%
- TuscanT;T 99%
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
rs7300972, a SNP in the SELPLG gene also known as M264V, is associated with risk for developing Non-Hodgkin Lymphoma based on a study of 458 patients. The odds ratio is 3.20 (CI: 1.48-6.91, p<0.01).
Source and license
Adapted from rs7300972 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.