rs7302230

A SNP in the CLSTN3 gene on chromosome 12. Its most notable genotype is A;A: common in complete genomics

Gene
CLSTN3
Location
Chr 127,135,836 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
2%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGoodcommon in complete genomicsTypical · 0.097% of people

On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 9 HapMap populations.

  • AverageA;A 97%
  • European ancestry (Utah)A;A 86%
  • Han Chinese (Beijing)A;A 100%
  • Japanese (Tokyo)A;A 100%
  • Yoruba (Nigeria)A;A 97%
  • African ancestry (Southwest US)A;A 98%
  • Luhya (Kenya)A;A 98%
  • Mexican ancestry (Los Angeles)A;A 97%
  • Maasai (Kenya)A;A 99%
  • TuscanA;A 94%

Conditions, medicines and genes

Notes

From SNPedia

Notes

According to a 2007 report, each G allele at rs7302230 in the CLSTN3 gene is associated with 1.6x higher odds of ankylosing spondylitis.

Source and license

Adapted from rs7302230 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.