rs732774
A SNP in the ATP7B gene on chromosome 13. Its most notable genotype is C;C: common in clinvar
- Gene
- ATP7B
- Location
- Chr 1351,949,672 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 48%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs732774 on the minus strand: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 28%
- European ancestry (Utah)C;C 19%
- Han Chinese (Beijing)C;C 36%
- Japanese (Tokyo)C;C 50%
- Yoruba (Nigeria)C;C 19%
- African ancestry (Southwest US)C;C 34%
- Chinese (Denver)C;C 32%
- Gujarati IndianC;C 35%
- Luhya (Kenya)C;C 21%
- Mexican ancestry (Los Angeles)C;C 19%
- Maasai (Kenya)C;C 31%
- TuscanC;C 18%
Related
Other ATP7B SNPs
- rs28942074A;AWilson's disease; variable age of onsetVery important
- rs76151636T;TWilson's disease; variable age of onsetVery important
- rs28942075C;TCarrier of a Wilson disease mutationImportant
- rs28942076C;TCarrier of a Wilson disease mutationImportant
- rs60431989A;GCarrier of a Wilson disease mutationImportant
- rs72552255A;GCarrier of a Wilson disease mutationImportant
- rs121907990C;TCarrier of a Wilson disease mutationImportant
- rs121907992C;TCarrier of a Wilson disease mutationImportant
Source and license
Adapted from rs732774 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.