rs74315448
A SNP in the KCNE2 gene on chromosome 21. Its most notable genotype is T;T: common in clinvar
- Gene
- KCNE2
- Location
- Chr 2134,370,648 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- <1%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Notes
From SNPedia
Notes
MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. A common polymorphism associated with antibiotic-induced cardiac arrhythmia. Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients. Spectrum of pathogenic mutations and associated polymorphisms in a cohort of 44 unrelated patients with long QT syndrome. Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test.
Source and license
Adapted from rs74315448 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.