rs743616
A SNP in the ARSA gene on chromosome 22. Its most notable genotype is G;G: common in clinvar
- Gene
- ARSA
- Location
- Chr 2250,625,611 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- 43%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageG;G 35%
- European ancestry (Utah)G;G 22%
- Han Chinese (Beijing)G;G 44%
- Japanese (Tokyo)G;G 39%
- Yoruba (Nigeria)G;G 37%
Related
Other ARSA SNPs
- rs6151429C;Cpseudoarylsulfatase A deficiency (possible)Important
- rs74315472A;Amiscalled by 23andMe; otherwise, when correct, Metachromatic leukodystrophy alleleImportant
- rs28940893A;GCarrier of a metachromatic leukodystrophy mutationImportant
- rs74315455C;TCarrier of a metachromatic leukodystrophy mutationImportant
- rs74315467A;GCarrier of a metachromatic leukodystrophy mutationImportant
- rs80338815C;TCarrier of a metachromatic leukodystrophy mutationImportant
- rs2071421T;Tcommon in clinvarTypical
Source and license
Adapted from rs743616 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.