rs7482144
A SNP in the HBG1 gene on chromosome 11. Its most notable genotype is G;G: common in clinvar
- Gene
- HBG1
- Location
- Chr 115,250,015 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 17%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Notes
From SNPedia
Notes
A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. Genetic complexity in sickle cell disease. Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients. Genetic modifiers of Hb E/beta0 thalassemia identified by a two-stage genome-wide association study. Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.
Source and license
Adapted from rs7482144 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.