rs7503034
A SNP in the SGSH gene on chromosome 17. Its most notable genotype is C;T: Benign (harmless) variant
- Gene
- SGSH
- Location
- Chr 1780,210,594 (GRCh38)
- Highest magnitude
- 0.1Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 33%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- C;TMost notableGoodBenign (harmless) variant
- T;TGoodBenign (harmless) variant
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;C 48% C;T 41% T;T 11%
- European ancestry (Utah)C;C 50% C;T 43% T;T 6%
- Han Chinese (Beijing)C;C 39% C;T 47% T;T 14%
- Japanese (Tokyo)C;C 51% C;T 40% T;T 9%
- Yoruba (Nigeria)C;C 59% C;T 37% T;T 4%
- African ancestry (Southwest US)C;C 67% C;T 25% T;T 9%
- Chinese (Denver)C;C 38% C;T 44% T;T 18%
- Gujarati IndianC;C 39% C;T 48% T;T 14%
- Luhya (Kenya)C;C 66% C;T 29% T;T 6%
- Mexican ancestry (Los Angeles)C;C 28% C;T 52% T;T 21%
- Maasai (Kenya)C;C 60% C;T 34% T;T 7%
- TuscanC;C 37% C;T 52% T;T 11%
Related
Other SGSH SNPs
- rs104894635T;TSanfilippo syndrome type AVery important
- rs104894637C;CSanfilippo syndrome type AVery important
- rs144143780C;CSanfilippo syndrome type AVery important
- rs770947426-;-Sanfilippo syndrome type AVery important
- rs34520362A;GCarrier of a Sanfilippo syndrome type A mutationImportant
- rs104894636A;GCarrier of a Sanfilippo syndrome type A mutationImportant
- rs104894638C;TCarrier of a Sanfilippo syndrome type A mutationImportant
- rs104894639C;TCarrier of a Sanfilippo syndrome type A mutationImportant
Notes
From SNPedia
Notes
Benign variant.
Source and license
Adapted from rs7503034 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.