rs7524102
A SNP in the ZBTB40 gene on chromosome 1. Its most notable genotype is A;A: common in complete genomics
- Gene
- ZBTB40
- Location
- Chr 122,371,954 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 23%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (A;A). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 58%
- European ancestry (Utah)A;A 65%
- Han Chinese (Beijing)A;A 55%
- Japanese (Tokyo)A;A 58%
- Yoruba (Nigeria)A;A 35%
- African ancestry (Southwest US)A;A 54%
- Chinese (Denver)A;A 66%
- Gujarati IndianA;A 67%
- Luhya (Kenya)A;A 43%
- Mexican ancestry (Los Angeles)A;A 85%
- Maasai (Kenya)A;A 39%
- TuscanA;A 69%
Notes
From SNPedia
Show notes, about 120 words
rs7524102 increases susceptibility to Bone mineral density variations, lower for carriers of the A allele rs7524102 increases susceptibility to Osteoporotic fractures 1.12 times for carriers of the A allele Common variants in the region around Osterix are associated with bone mineral density and growth in childhood. Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening. OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts. Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.
Source and license
Adapted from rs7524102 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.