rs7531806

A SNP in the LOC107985745 gene on chromosome 1. Its most notable genotype is A;A: Slightly (1.4x) increased risk of acne occurrences in Chinese Han population.

Gene
LOC107985745
Location
Chr 1169,681,903 (GRCh38)
Highest magnitude
1.4Minor
Tested on
23andMe, AncestryDNA, FamilyTreeDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBadSlightly (1.4x) increased risk of acne occurrences in Chinese Han population.Minor · 1.439% of people
  2. A;GBadVery slightly increased risk of acne occurrences in Han Chinese studyMinor · 1.141% of people
  3. G;GGoodcommon/normalTypical · 0.020% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 39% A;G 41% G;G 20%
  • European ancestry (Utah)A;A 36% A;G 44% G;G 20%
  • Han Chinese (Beijing)A;A 18% A;G 50% G;G 31%
  • Japanese (Tokyo)A;A 19% A;G 45% G;G 36%
  • Yoruba (Nigeria)A;A 66% A;G 30% G;G 4%
  • African ancestry (Southwest US)A;A 58% A;G 32% G;G 11%
  • Chinese (Denver)A;A 22% A;G 44% G;G 34%
  • Gujarati IndianA;A 30% A;G 49% G;G 22%
  • Luhya (Kenya)A;A 67% A;G 26% G;G 6%
  • Mexican ancestry (Los Angeles)A;A 19% A;G 55% G;G 26%
  • Maasai (Kenya)A;A 58% A;G 34% G;G 8%
  • TuscanA;A 37% A;G 43% G;G 20%

Notes

From SNPedia

Notes

Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne.

A;A

Decreased risk of acne occurrences in Chinese Han population {{PMID|24399259}OA=1}}.

References

Source and license

Adapted from rs7531806 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.