rs762551(A;A)

Faster caffeine metabolism in smokers and heavy coffee consumers

Magnitude
1.5Minor
Repute
Not rated
Frequency
38%Average of 11 populations
On SNPedia
rs762551(A;A)
Gene
CYP1A2

Frequency

Share of people with A;A in each HapMap population.

  • Mexican ancestry (Los Angeles)59%
  • European ancestry (Utah)53%
  • Han Chinese (Beijing)45%
  • African ancestry (Southwest US)44%
  • Tuscan39%
  • Chinese (Denver)36%
  • Japanese (Tokyo)35%
  • Yoruba (Nigeria)33%
  • Maasai (Kenya)28%
  • Gujarati Indian26%
  • Luhya (Kenya)20%

Other genotypes of rs762551

  1. A;CNot ratedCarrier of one CYP1A2*1F allele; Normal metabolism of caffeineTypical · 0.046% of people
  2. C;CNot ratedNormal metabolism of caffeine.Typical · 0.016% of people

All about rs762551

Notes

From SNPedia

Highly inducible form of CYP1A2 enzyme. 1.6x faster caffeine metabolism in smokers. 1.4x faster caffeine metabolism in heavy coffee consumers (more than 3 cups).

Source and license

Adapted from rs762551(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.