rs76546355
A SNP on chromosome 6. Its most notable genotype is A;A: increased risk of Behçet's disease
- Gene
- None listed
- Location
- Chr 631,381,371 (GRCh38)
- Highest magnitude
- 5.5Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- A;AMost notableBadincreased risk of Behçet's disease
- A;GBadincreased risk of Behçet's disease
- G;GGoodcommon in complete genomics
On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Notes
From SNPedia
Show notes, about 160 words
rs76546355 (A) is a risk allele for Behçet's disease. HLA-B*51 allele and the rs76546355 MHC SNP are independent genetic risk factors for Behçet's disease in Iranian, and that positivity for the rs76546355 risk allele, but not for B*51, does correlate with specific demographic characteristics or clinical manifestations in Behçet's disease patients
A;A
HLA-B*51 allele and the rs76546355 MHC SNP are independent genetic risk factors for Behçet's disease in Iranian, and that positivity for the rs76546355 risk allele, but not for B*51, does correlate with specific demographic characteristics or clinical manifestations in Behçet's disease patients
A;G
HLA-B*51 allele and the rs76546355 MHC SNP are independent genetic risk factors for Behçet's disease in Iranian, and that positivity for the rs76546355 risk allele, but not for B*51, does correlate with specific demographic characteristics or clinical manifestations in Behçet's disease patients
Source and license
Adapted from rs76546355 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.