rs7759938

A SNP on chromosome 6. Its most notable genotype is C;C: age at menarche ~2 months later on average

Gene
None listed
Location
Chr 6104,931,079 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
39%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedage at menarche ~2 months later on averageTypical · 0.017% of people
  2. C;TNot ratedage at menarche ~1 month later on averageTypical · 0.047% of people
  3. T;TNot ratednormalTypical · 0.036% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 17% C;T 47% T;T 36%
  • European ancestry (Utah)C;C 7% C;T 58% T;T 35%
  • Han Chinese (Beijing)C;C 8% C;T 38% T;T 54%
  • Japanese (Tokyo)C;C 2% C;T 50% T;T 49%
  • Yoruba (Nigeria)C;C 37% C;T 46% T;T 16%
  • African ancestry (Southwest US)C;C 25% C;T 60% T;T 16%
  • Chinese (Denver)C;C 7% C;T 47% T;T 46%
  • Gujarati IndianC;C 12% C;T 48% T;T 41%
  • Luhya (Kenya)C;C 46% C;T 45% T;T 10%
  • Mexican ancestry (Los Angeles)C;C 5% C;T 38% T;T 57%
  • Maasai (Kenya)C;C 29% C;T 50% T;T 21%
  • TuscanC;C 11% C;T 42% T;T 47%

Notes

From SNPedia

Notes

rs7759938 is a SNP from chromosomal region 6q21 showing a strong association with age at menarche in a study of 17,500 Icelandic women. Per copy carried of the rs7759938(T) allele, age at menarche is delayed about 1 month. Distinct variants at LIN28B influence growth in height from birth to adulthood.

Source and license

Adapted from rs7759938 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.