rs7776725

A SNP in the FAM3C gene on chromosome 7. Its most notable genotype is C;C: weaker bones

Gene
FAM3C
Location
Chr 7121,393,067 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
25%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBadweaker bonesWorth knowing · 2.08% of people
  2. T;TGoodstronger bonesWorth knowing · 2.055% of people

On SNPedia: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 8% T;T 55%
  • European ancestry (Utah)C;C 11% T;T 55%
  • Han Chinese (Beijing)C;C <1% T;T 79%
  • Japanese (Tokyo)C;C 3% T;T 76%
  • Yoruba (Nigeria)C;C 10% T;T 44%
  • African ancestry (Southwest US)C;C 19% T;T 35%
  • Chinese (Denver)C;C 2% T;T 79%
  • Gujarati IndianC;C 3% T;T 62%
  • Luhya (Kenya)C;C 12% T;T 43%
  • Mexican ancestry (Los Angeles)C;C 12% T;T 52%
  • Maasai (Kenya)C;C 12% T;T 37%
  • TuscanC;C 8% T;T 49%

Notes

From SNPedia

Notes

Korean bone mineral density rs7776725 and rs1721400

Source and license

Adapted from rs7776725 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.