rs7816345

A SNP in the RPL26P25 gene on chromosome 8. Its most notable genotype is C;C: bigger breast size (normal in European)

Gene
RPL26P25
Location
Chr 836,988,591 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
27%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableNot ratedbigger breast size (normal in European)Worth knowing · 2.048% of people
  2. C;TNot ratedSlightly (0.15th cup) smaller breast size on averageWorth knowing · 2.042% of people
  3. T;TNot ratedSlightly (0.3 of a cup) smaller breast size on averageWorth knowing · 2.010% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 48% C;T 42% T;T 10%
  • European ancestry (Utah)C;C 73% C;T 27% T;T 0%
  • Han Chinese (Beijing)C;C 49% C;T 38% T;T 13%
  • Japanese (Tokyo)C;C 39% C;T 48% T;T 13%
  • Yoruba (Nigeria)C;C 33% C;T 51% T;T 16%
  • African ancestry (Southwest US)C;C 35% C;T 53% T;T 12%
  • Chinese (Denver)C;C 46% C;T 41% T;T 13%
  • Gujarati IndianC;C 42% C;T 47% T;T 12%
  • Luhya (Kenya)C;C 34% C;T 55% T;T 11%
  • Mexican ancestry (Los Angeles)C;C 60% C;T 38% T;T 2%
  • Maasai (Kenya)C;C 59% C;T 31% T;T 10%
  • TuscanC;C 60% C;T 33% T;T 7%

Notes

From SNPedia

Notes

breast size

Source and license

Adapted from rs7816345 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.