rs7868992

A SNP in the COL27A1 gene on chromosome 9. Its most notable genotype is A;A: 1.29x risk of Tourette's Syndrome

Gene
COL27A1
Location
Chr 9114,228,791 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
46%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBad1.29x risk of Tourette's SyndromeTypical · 0.031% of people
  2. A;GBad1.29x risk of Tourette's SyndromeTypical · 0.043% of people
  3. G;GGoodnormalTypical · 0.026% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 31% A;G 43% G;G 26%
  • European ancestry (Utah)A;A 50% A;G 44% G;G 6%
  • Han Chinese (Beijing)A;A 11% A;G 53% G;G 36%
  • Japanese (Tokyo)A;A 6% A;G 42% G;G 52%
  • Yoruba (Nigeria)A;A 21% A;G 46% G;G 33%
  • African ancestry (Southwest US)A;A 23% A;G 48% G;G 29%
  • Chinese (Denver)A;A 14% A;G 42% G;G 44%
  • Gujarati IndianA;A 76% A;G 21% G;G 3%
  • Luhya (Kenya)A;A 26% A;G 47% G;G 26%
  • Mexican ancestry (Los Angeles)A;A 45% A;G 47% G;G 9%
  • Maasai (Kenya)A;A 20% A;G 45% G;G 36%
  • TuscanA;A 44% A;G 43% G;G 13%

Source and license

Adapted from rs7868992 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.