rs7927894

A SNP on chromosome 11. Its most notable genotype is C;C: 0.83x lower risk of Atopic Dermatitis.

Gene
None listed
Location
Chr 1176,590,272 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
28%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGood0.83x lower risk of Atopic Dermatitis.Worth knowing · 2.052% of people
  2. C;TGoodNormal risk of Atopic Dermatitis.Minor · 1.939% of people
  3. T;TBad1.2x higher risk of Atopic Dermatitis.Worth knowing · 2.08% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 52% C;T 39% T;T 8%
  • European ancestry (Utah)C;C 39% C;T 43% T;T 18%
  • Han Chinese (Beijing)C;C 63% C;T 33% T;T 4%
  • Japanese (Tokyo)C;C 72% C;T 27% T;T 2%
  • Yoruba (Nigeria)C;C 47% C;T 42% T;T 11%
  • African ancestry (Southwest US)C;C 42% C;T 56% T;T 2%
  • Chinese (Denver)C;C 62% C;T 35% T;T 4%
  • Gujarati IndianC;C 57% C;T 35% T;T 8%
  • Luhya (Kenya)C;C 53% C;T 38% T;T 9%
  • Mexican ancestry (Los Angeles)C;C 55% C;T 38% T;T 7%
  • Maasai (Kenya)C;C 52% C;T 38% T;T 10%
  • TuscanC;C 34% C;T 49% T;T 17%

Notes

From SNPedia

Notes

23andMe blog associated rs7927894(T) with Crohn’s disease 1.16x and atopic dermatitis

C;C

Verified in Asians.

T;T

Verified in Asians.

Source and license

Adapted from rs7927894 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.