rs798766

A SNP in the TACC3 gene on chromosome 4. Its most notable genotype is T;T: Increased susceptibility urinary bladder cancer

Gene
TACC3
Location
Chr 41,732,512 (GRCh38)
Highest magnitude
1.0Minor
Tested on
23andMe, AncestryDNA
Minor allele frequency
22%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. T;TMost notableBadIncreased susceptibility urinary bladder cancerMinor · 1.07% of people

On SNPedia: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageT;T 7%
  • European ancestry (Utah)T;T 3%
  • Han Chinese (Beijing)T;T 2%
  • Japanese (Tokyo)T;T 7%
  • Yoruba (Nigeria)T;T 8%
  • African ancestry (Southwest US)T;T 9%
  • Chinese (Denver)T;T 5%
  • Gujarati IndianT;T 5%
  • Luhya (Kenya)T;T 16%
  • Mexican ancestry (Los Angeles)T;T 10%
  • Maasai (Kenya)T;T 11%
  • TuscanT;T 4%

Conditions, medicines and genes

Notes

From SNPedia

Notes

The T allele at rs798766 is associated with 1.24 higher odds of bladder cancer.

Source and license

Adapted from rs798766 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.