rs8038652

A SNP in the IQCH gene on chromosome 15. Its most notable genotype is A;A: shorter adult height, at least among Mongolians

Gene
IQCH
Location
Chr 1567,259,726 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
28%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedshorter adult height, at least among MongoliansTypical · 0.011% of people
  2. A;GNot ratednormalTypical · 0.033% of people
  3. G;GNot ratednormalTypical · 0.057% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 11% A;G 33% G;G 57%
  • European ancestry (Utah)A;A 6% A;G 33% G;G 61%
  • Han Chinese (Beijing)A;A 28% A;G 47% G;G 26%
  • Japanese (Tokyo)A;A 23% A;G 45% G;G 32%
  • Yoruba (Nigeria)A;A <1% A;G 13% G;G 86%
  • African ancestry (Southwest US)A;A 0% A;G 26% G;G 74%
  • Chinese (Denver)A;A 20% A;G 43% G;G 37%
  • Gujarati IndianA;A 12% A;G 32% G;G 56%
  • Luhya (Kenya)A;A 0% A;G 16% G;G 85%
  • Mexican ancestry (Los Angeles)A;A 19% A;G 43% G;G 38%
  • Maasai (Kenya)A;A 1% A;G 25% G;G 74%
  • TuscanA;A 7% A;G 38% G;G 55%

Notes

From SNPedia

Notes

A study of 1,000+ Mongolian adults divided between tall (> 177cm) and short (< 155cm) individuals found a strong association (p = 0.0003) between rs8038652 and adult height. The (A;A) genotype was most strongly associated under a recessive model with shorter adult height (p = 0.000046).

Source and license

Adapted from rs8038652 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.