rs8053188
A SNP in the PALB2 gene on chromosome 16. Its most notable genotype is C;C: common in complete genomics
- Gene
- PALB2
- Location
- Chr 1623,641,204 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe
- Minor allele frequency
- 4%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CMost notableGoodcommon in complete genomics
- C;TNot ratedConsidered benign in ClinVar
- T;TNot ratedConsidered benign in ClinVar
On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;C 90% C;T 10% T;T <1%
- European ancestry (Utah)C;C 91% C;T 9% T;T 0%
- Han Chinese (Beijing)C;C 96% C;T 4% T;T 0%
- Japanese (Tokyo)C;C 98% C;T 2% T;T 0%
- Yoruba (Nigeria)C;C 74% C;T 24% T;T 2%
Related
Other PALB2 SNPs
- rs118203997T;TFanconi anemia, complementation group NVery important
- rs118203998C;CFanconi anemia, complementation group NVery important
- rs118203999A;AFanconi anemia, complementation group NVery important
- rs180177083A;AFanconi anemia, complementation group NVery important
- rs180177084-;-Fanconi anemia, complementation group NVery important
- rs180177085-;-Fanconi anemia, complementation group NVery important
- rs180177090-;-Fanconi anemia, complementation group NVery important
- rs180177091A;AFanconi anemia, complementation group NVery important
Source and license
Adapted from rs8053188 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.