rs8085664

A SNP in the SLC14A2 gene on chromosome 18. Its most notable genotype is A;A: 0.61x reduced risk of Male Pattern Baldness.

Gene
SLC14A2
Location
Chr 1845,234,191 (GRCh38)
Highest magnitude
2.1Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
30%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableGood0.61x reduced risk of Male Pattern Baldness.Worth knowing · 2.113% of people
  2. A;CGood0.78x reduced risk of Male Pattern Baldness.Worth knowing · 2.039% of people
  3. C;CBadNormal (higher) risk of Male Pattern Baldness.Minor · 1.748% of people

On SNPedia: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 13% A;C 39% C;C 48%
  • European ancestry (Utah)A;A 11% A;C 41% C;C 49%
  • Han Chinese (Beijing)A;A 2% A;C 39% C;C 60%
  • Japanese (Tokyo)A;A <1% A;C 31% C;C 68%
  • Yoruba (Nigeria)A;A 20% A;C 47% C;C 33%
  • African ancestry (Southwest US)A;A 19% A;C 39% C;C 42%
  • Chinese (Denver)A;A <1% A;C 32% C;C 67%
  • Gujarati IndianA;A 3% A;C 24% C;C 73%
  • Luhya (Kenya)A;A 32% A;C 54% C;C 15%
  • Mexican ancestry (Los Angeles)A;A 17% A;C 41% C;C 41%
  • Maasai (Kenya)A;A 33% A;C 49% C;C 18%
  • TuscanA;A 7% A;C 36% C;C 57%

Conditions, medicines and genes

Other SLC14A2 SNPs

All SLC14A2 SNPs

Notes

From SNPedia

Notes

This is the 23andWe discovery: "Male Pattern Baldness: Preliminary Research". It affects appearance.

A;A

Discovered by 23andWe based on customer surveys, and considered preliminary research.

A;C

Discovered by 23andWe based on customer surveys, and considered preliminary research.

C;C

Discovered by 23andWe based on customer surveys, and considered preliminary research.

Source and license

Adapted from rs8085664 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.