rs8111071

A SNP in the RSPH6A gene on chromosome 19. Its most notable genotype is A;A: normal

Gene
RSPH6A
Location
Chr 1945,804,148 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
3%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratednormalTypical · 0.093% of people
  2. A;GNot rated1.5x riskTypical · 0.06% of people
  3. G;GNot rated1.3x riskTypical · 0.0<1% of people

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageA;A 93% A;G 6% G;G <1%
  • European ancestry (Utah)A;A 83% A;G 17% G;G 0%
  • Han Chinese (Beijing)A;A 99% A;G <1% G;G 0%
  • Japanese (Tokyo)A;A 100% A;G 0% G;G 0%
  • Yoruba (Nigeria)A;A 100% A;G 0% G;G 0%
  • African ancestry (Southwest US)A;A 93% A;G 7% G;G 0%
  • Gujarati IndianA;A 95% A;G 5% G;G 0%
  • Luhya (Kenya)A;A 99% A;G <1% G;G 0%
  • Mexican ancestry (Los Angeles)A;A 88% A;G 10% G;G 2%
  • Maasai (Kenya)A;A 89% A;G 12% G;G 0%
  • TuscanA;A 88% A;G 12% G;G 0%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs8111071 has been reported in a large study to be associated with Crohn's disease. The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.47 (CI 1.25-1.73), and for homozygotes, 1.28 (CI 0.56-2.88).

Source and license

Adapted from rs8111071 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.