rs885822
A SNP in the PRF1 gene on chromosome 10. Its most notable genotype is G;G: common in clinvar
- Gene
- PRF1
- Location
- Chr 1070,598,821 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA, FamilyTreeDNA
- Minor allele frequency
- 31%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs885822 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageG;G 10%
- European ancestry (Utah)G;G 15%
- Han Chinese (Beijing)G;G 11%
- Japanese (Tokyo)G;G 7%
- Yoruba (Nigeria)G;G 1%
- African ancestry (Southwest US)G;G 5%
- Chinese (Denver)G;G 8%
- Gujarati IndianG;G 19%
- Luhya (Kenya)G;G 2%
- Mexican ancestry (Los Angeles)G;G 16%
- Maasai (Kenya)G;G 4%
- TuscanG;G 24%
Related
Other PRF1 SNPs
- rs28933375C;CFamilial Hemophagocytic Lymphohistiocytosis and LymphomaVery important
- rs28933374A;GCarrier of a hemophagocytic lymphohistiocytosis (HLH) mutationImportant
- rs28933376A;GCarrier of a hemophagocytic lymphohistiocytosis (HLH) mutationImportant
- rs28933973A;GCarrier of a hemophagocytic lymphohistiocytosis (HLH) mutationImportant
- rs104894176C;TCarrier of a hemophagocytic lymphohistiocytosis (HLH) mutationImportant
- rs104894180A;GCarrier of a hemophagocytic lymphohistiocytosis (HLH) mutationImportant
- rs104894181C;TCarrier of a hemophagocytic lymphohistiocytosis (HLH) mutationImportant
- rs104894182C;TCarrier of a hemophagocytic lymphohistiocytosis (HLH) mutationImportant
Source and license
Adapted from rs885822 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.