rs912428
A SNP in the LRCH1 gene on chromosome 13. Its most notable genotype is G;G: common in complete genomics
- Gene
- LRCH1
- Location
- Chr 1346,593,768 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 13%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs912428 on the minus strand: (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageG;G 77%
- European ancestry (Utah)G;G 65%
- Han Chinese (Beijing)G;G 80%
- Japanese (Tokyo)G;G 77%
- Yoruba (Nigeria)G;G 86%
Notes
From SNPedia
Notes
Association between a variation in LRCH1 and knee osteoarthritis: a genome-wide single-nucleotide polymorphism association study using DNA pooling. Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility. Field synopsis and synthesis of genetic association studies in osteoarthritis: the CUMAGAS-OSTEO information system.
Source and license
Adapted from rs912428 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.