rs9271588

A SNP on chromosome 6. Its most notable genotype is C;C: 0.57x risk for Sjogren's syndrome

Gene
None listed
Location
Chr 632,623,176 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableGood0.57x risk for Sjogren's syndromeTypical · 0.019% of people
  2. C;TGood0.57x risk for Sjogren's syndromeTypical · 0.049% of people
  3. T;TNot ratednormalTypical · 0.033% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 19% C;T 49% T;T 33%
  • European ancestry (Utah)C;C 37% C;T 43% T;T 20%
  • Han Chinese (Beijing)C;C 19% C;T 56% T;T 26%
  • Japanese (Tokyo)C;C 26% C;T 50% T;T 24%
  • Yoruba (Nigeria)C;C 12% C;T 41% T;T 48%
  • African ancestry (Southwest US)C;C 16% C;T 53% T;T 32%
  • Chinese (Denver)C;C 24% C;T 48% T;T 28%
  • Gujarati IndianC;C 21% C;T 51% T;T 29%
  • Luhya (Kenya)C;C 6% C;T 40% T;T 55%
  • Mexican ancestry (Los Angeles)C;C 17% C;T 55% T;T 28%
  • Maasai (Kenya)C;C 16% C;T 52% T;T 32%
  • TuscanC;C 14% C;T 47% T;T 39%

Source and license

Adapted from rs9271588 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.