rs9469220

A SNP on chromosome 6. Its most notable genotype is A;A: 1.5x risk of Crohn's disease

Gene
None listed
Location
Chr 632,690,533 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA
Minor allele frequency
42%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableBad1.5x risk of Crohn's diseaseTypical · 0.036% of people
  2. A;GBad1.1x risk of Crohn's diseaseTypical · 0.047% of people
  3. C;CNot ratedNo summary available.Typical · 0.00% of people
  4. G;GNot ratednormalTypical · 0.017% of people

On SNPedia: (A;A), (A;G), (C;C), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 36% A;G 47% C;C 0% G;G 17%
  • European ancestry (Utah)A;A 20% A;G 48% C;C 0% G;G 32%
  • Han Chinese (Beijing)A;A 44% A;G 44% C;C 0% G;G 12%
  • Japanese (Tokyo)A;A 45% A;G 46% C;C 0% G;G 9%
  • Yoruba (Nigeria)A;A 29% A;G 50% C;C 0% G;G 22%
  • African ancestry (Southwest US)A;A 37% A;G 44% C;C 0% G;G 19%
  • Chinese (Denver)A;A 48% A;G 41% C;C 0% G;G 11%
  • Gujarati IndianA;A 42% A;G 42% C;C 0% G;G 17%
  • Luhya (Kenya)A;A 36% A;G 49% C;C 0% G;G 16%
  • Mexican ancestry (Los Angeles)A;A 31% A;G 57% C;C 0% G;G 12%
  • Maasai (Kenya)A;A 21% A;G 54% C;C 0% G;G 25%
  • TuscanA;A 41% A;G 44% C;C 0% G;G 16%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs9469220 has been reported in a large study to be associated with Crohn's disease. The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with heterozygotes is 1.14 (CI 0.98-1.32), and for homozygotes, 1.52 (CI 1.28-1.79).

Source and license

Adapted from rs9469220 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.