rs9527025
A SNP in the KL gene on chromosome 13. Its most notable genotype is C;G: Intelligence; Ageing; Longevity
- Gene
- KL
- Location
- Chr 1333,054,056 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- AncestryDNA
- Minor allele frequency
- 13%
Genotypes
As shown in 23andMe and AncestryDNA files.
On SNPedia: (C;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 4 HapMap populations.
- AverageC;G 17% G;G 82%
- European ancestry (Utah)C;G 29% G;G 69%
- Han Chinese (Beijing)C;G 0% G;G 100%
- Japanese (Tokyo)C;G 0% G;G 100%
- Yoruba (Nigeria)C;G 38% G;G 60%
Related
Other KL SNPs
- rs9536314G;G2 copies of KL-VS haplotype; one report links this to lower cognitive function with ageMinor
- rs211239G;G1.7x risk for priapism in SCA patientsTypical
- rs648202T;Tcommon in clinvarTypical
- rs2249358A;Anormal risk for priapism in SCA patientsTypical
- rs3752472C;Ccommon in complete genomicsTypical
Notes
From SNPedia
Notes
C;G
"Klotho" gene. http://www.ashg.org/2013meeting/abstracts/fulltext/f130122721.htm http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?rs= http://www.sfgate.com/health/article/Smart-seniors-might-have-this-gene-variant-5463746.php
Source and license
Adapted from rs9527025 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.