rs9543325

A SNP on chromosome 13. Its most notable genotype is C;C: 1.37x Slightly higher pancreatic cancer risk

Gene
None listed
Location
Chr 1373,342,491 (GRCh38)
Highest magnitude
2.0Worth knowing
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
48%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CMost notableBad1.37x Slightly higher pancreatic cancer riskWorth knowing · 2.041% of people
  2. C;TBad1.37x increased risk of pancreatic cancerTypical · 0.034% of people
  3. T;TGoodnormal risk of pancreatic cancerTypical · 0.025% of people

On SNPedia: (C;C), (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 41% C;T 34% T;T 25%
  • European ancestry (Utah)C;C 6% C;T 50% T;T 43%
  • Han Chinese (Beijing)C;C 20% C;T 48% T;T 32%
  • Japanese (Tokyo)C;C 21% C;T 45% T;T 34%
  • Yoruba (Nigeria)C;C 97% C;T 3% T;T 0%
  • African ancestry (Southwest US)C;C 70% C;T 25% T;T 5%
  • Chinese (Denver)C;C 19% C;T 49% T;T 32%
  • Gujarati IndianC;C 9% C;T 37% T;T 55%
  • Luhya (Kenya)C;C 94% C;T 6% T;T 0%
  • Mexican ancestry (Los Angeles)C;C 10% C;T 47% T;T 43%
  • Maasai (Kenya)C;C 80% C;T 18% T;T 2%
  • TuscanC;C 19% C;T 48% T;T 33%

Conditions, medicines and genes

Notes

From SNPedia

Notes

The C allele of this SNP is ssociated with slightly higher risk of pancreatic cancer.

Source and license

Adapted from rs9543325 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.