rs964184

A SNP in the ZNF259 gene on chromosome 11. Its most notable genotype is G;G: increased risk of hypertriglyceridemia

Gene
ZNF259
Location
Chr 11116,778,201 (GRCh38)
Highest magnitude
2.2Worth knowing
Tested on
23andMe, AncestryDNA
Minor allele frequency
20%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. C;CNot ratedNo summary available.Typical · 0.062% of people
  2. G;GMost notableBadincreased risk of hypertriglyceridemiaWorth knowing · 2.24% of people

On SNPedia: (C;C), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageC;C 62% G;G 4%
  • European ancestry (Utah)C;C 77% G;G <1%
  • Han Chinese (Beijing)C;C 60% G;G 4%
  • Japanese (Tokyo)C;C 42% G;G 9%
  • Yoruba (Nigeria)C;C 65% G;G 3%
  • African ancestry (Southwest US)C;C 70% G;G 2%
  • Chinese (Denver)C;C 60% G;G 3%
  • Gujarati IndianC;C 66% G;G 4%
  • Luhya (Kenya)C;C 60% G;G 3%
  • Mexican ancestry (Los Angeles)C;C 50% G;G 5%
  • Maasai (Kenya)C;C 63% G;G 3%
  • TuscanC;C 68% G;G 8%

Conditions, medicines and genes

Other ZNF259 SNPs

All ZNF259 SNPs

Notes

From SNPedia

Notes

The rs964184(G;G) genotype is associated with hypertriglyceridemia.

Source and license

Adapted from rs964184 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.