rs975278(T;T)

1.5x higher risk for emphysema, higher in smokers

Magnitude
1.5Minor
Repute
Bad
Frequency
13%Average of 11 populations
On SNPedia
rs975278(A;A)Minus strand
Gene
SERPINE2

Frequency

Share of people with T;T in each HapMap population.

  • Japanese (Tokyo)35%
  • Chinese (Denver)29%
  • Han Chinese (Beijing)28%
  • Gujarati Indian11%
  • Luhya (Kenya)11%
  • Yoruba (Nigeria)10%
  • African ancestry (Southwest US)9%
  • Maasai (Kenya)5%
  • Tuscan4%
  • European ancestry (Utah)3%
  • Mexican ancestry (Los Angeles)2%

Other genotypes of rs975278

  1. C;TNot ratedNo summary available.Typical · 0.040% of people
  2. C;CNot ratednormalTypical · 0.047% of people

All about rs975278

Source and license

Adapted from rs975278(A;A) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.