rs977785

A SNP in the LY86 gene on chromosome 6. Its most notable genotype is A;A: average

Gene
LY86
Location
Chr 66,588,648 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
30%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedaverageTypical · 0.09% of people
  2. A;CNot ratedincreased riskTypical · 0.045% of people
  3. C;CNot ratedincreased riskTypical · 0.046% of people

On SNPedia: (A;A), (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageA;A 9% A;C 45% C;C 46%
  • European ancestry (Utah)A;A 6% A;C 47% C;C 47%
  • Han Chinese (Beijing)A;A 13% A;C 47% C;C 40%
  • Japanese (Tokyo)A;A 9% A;C 43% C;C 48%
  • Yoruba (Nigeria)A;A 11% A;C 52% C;C 37%
  • African ancestry (Southwest US)A;A 11% A;C 46% C;C 44%
  • Chinese (Denver)A;A 11% A;C 48% C;C 41%
  • Gujarati IndianA;A 3% A;C 34% C;C 63%
  • Luhya (Kenya)A;A 14% A;C 51% C;C 36%
  • Mexican ancestry (Los Angeles)A;A 9% A;C 43% C;C 48%
  • Maasai (Kenya)A;A 15% A;C 46% C;C 39%
  • TuscanA;A 4% A;C 37% C;C 59%

Conditions, medicines and genes

Other LY86 SNPs

All LY86 SNPs

Notes

From SNPedia

Notes

rs977785, a SNP purported to be in the promoter of the LY86 gene, is reported to be associated with mite-sensitive allergies in children, based on a study of 500+ Taiwanese patients. The allele that is underrepresented (and thus protective?) is the minor allele, which in dbSNP orientation is rs1334710(A).

Source and license

Adapted from rs977785 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.