i4001456

A SNP in the CYP2D6 gene on chromosome 22. Its most notable genotype is A;A: Homozygous for CYP2D6*4F non-functioning variant

Gene
CYP2D6
Location
Chr 2242,524,935 (GRCh38)
Highest magnitude
3.5Important
Tested on
23andMe

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AMost notableNot ratedHomozygous for CYP2D6*4F non-functioning variantImportant · 3.5
  2. A;GNot ratedCarrier of one copy of CYP2D6*4F non-functioning variant.Worth knowing · 2.0
  3. G;GGoodnormalTypical · 0.0

On SNPedia: (A;A), (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other CYP2D6 SNPs

All CYP2D6 SNPs

Notes

From SNPedia

Notes

Also known as 1858C>T, the (A) allele is a marker for CYP2D6*4F non-functioning variant.

Source and license

Adapted from i4001456 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.