i5009373

A SNP. Its most notable genotype is A;C: BRCA2 mutation considered pathogenic for breast cancer

Gene
None listed
Highest magnitude
6.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;CMost notableBadBRCA2 mutation considered pathogenic for breast cancerVery important · 6.0
  2. C;CGoodnormalTypical · 0.0

On SNPedia: (A;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

For information about causal/pathogenic BRCA2 mutations and what they imply about the odds of developing breast cancer, please see the BRCA2 page and links from that page.

A;C

see discussion at rs80358824

Source and license

Adapted from i5009373 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.