i5010469

A SNP. Its most notable genotype is D;I: likely to be BRCA2 variant formerly thought to be pathogenic for breast cancer

Gene
None listed
Highest magnitude
3.0Important
Tested on
23andMe

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. D;DGoodnormalTypical · 0.0
  2. D;IMost notableBadlikely to be BRCA2 variant formerly thought to be pathogenic for breast cancerImportant · 3.0

On SNPedia: (D;D), (D;I). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

For information about causal/pathogenic BRCA2 mutations and what they imply about the odds of developing breast cancer, please see the BRCA2 page and links from that page.

D;I

Although this SNP appears to be rs397507736, a mutation thought at one time to be pathogenic for breast cancer, due to secrecy policies at 23andMe it is not confirmed.

Source and license

Adapted from i5010469 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.