i5010634

A SNP. Its most notable genotype is A;C: possibly a Cystic Fibrosis carrier

Gene
None listed
Highest magnitude
3.5Important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;AGoodcommon/normalTypical · 0.0
  2. A;CMost notableBadpossibly a Cystic Fibrosis carrierImportant · 3.5

On SNPedia: (A;A), (A;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

Cystic Fibrosis rs397508328

A;C

This could be an error in 23andMe's database, when they should have entered the variant genotype as (A;G) rather than (A;C). The effect of the (A;C) genotype is unknown, however, an (A;G) genotype at this SNP is considered being a carrier of a pathogenic Cystic Fibrosis allele.

Source and license

Adapted from i5010634 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.