i5053894
A SNP. Its most notable genotype is D;I: likely to be BRCA2 variant pathogenic for breast cancer
- Gene
- None listed
- Highest magnitude
- 6.0Very important
- Tested on
- 23andMe
Genotypes
As shown in 23andMe and AncestryDNA files.
- D;IMost notableBadlikely to be BRCA2 variant pathogenic for breast cancer
- I;IGoodnormal
On SNPedia: (D;I), (I;I). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Conditions, medicines and genes
Notes
From SNPedia
Notes
For information about causal/pathogenic BRCA2 mutations and what they imply about the odds of developing breast cancer, please see the BRCA2 page and links from that page. Note that the equivalence of i5053894 with rs80359677 is an educated guess, which 23andMe will neither confirm nor deny.
D;I
Although this SNP appears to be rs80359677, a mutation pathogenic for breast cancer, due to secrecy policies at 23andMe it is not confirmed.
Source and license
Adapted from i5053894 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.