i6006959

A SNP. Its most notable genotype is T;T: hypophosphatasia

Gene
None listed
Highest magnitude
4.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GGoodnormalTypical · 0.0
  2. G;TBadcarrier of a hypophosphatasia alleleImportant · 3.0
  3. T;TMost notableBadhypophosphatasiaVery important · 4.0

On SNPedia: (G;G), (G;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

i6006959, also known as c.1276G>T or p.G426C, is a SNP in the ALPL gene on chromosome 1. Based on the ALPL gene mutations database, the rare/minor allele is considered pathogenic for the infantile form of hypophosphatasia.

Source and license

Adapted from i6006959 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.