rs1004467
A SNP in the CYP17A1 gene on chromosome 10. Its most notable genotype is A;A.
- Gene
- CYP17A1
- Location
- Chr 10102,834,750 (GRCh38)
- Highest magnitude
- 0.0Typical
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 20%
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
SNPedia records rs1004467 on the minus strand: (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageA;A 61%
- European ancestry (Utah)A;A 84%
- Han Chinese (Beijing)A;A 42%
- Japanese (Tokyo)A;A 49%
- Yoruba (Nigeria)A;A 66%
- African ancestry (Southwest US)A;A 65%
- Chinese (Denver)A;A 40%
- Gujarati IndianA;A 52%
- Luhya (Kenya)A;A 63%
- Mexican ancestry (Los Angeles)A;A 62%
- Maasai (Kenya)A;A 73%
- TuscanA;A 78%
Related
Conditions, medicines and genes
Other CYP17A1 SNPs
- rs104894135G;GComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894138A;AComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894141T;TComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894142A;AComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894143G;GComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894144C;CComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894145A;AComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
- rs104894146C;CComplete combined 17-alpha-hydroxylase/17,20-lyase deficiencyVery important
Notes
From SNPedia
Notes
23andMe blog blood pressure Common variants in or near FGF5, CYP17A1 and MTHFR genes are associated with blood pressure and hypertension in Chinese Hans.
Source and license
Adapted from rs1004467 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.