rs1011490341

A SNP. Its most notable genotype is C;G: Reported to lead to nocturnal paroxysmal atrial fibrillation

Gene
None listed
Highest magnitude
5.0Very important
Tested on
Not on consumer chips

Genotypes

As shown in 23andMe and AncestryDNA files.

On SNPedia: (C;C), (C;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Conditions, medicines and genes

Notes

From SNPedia

Notes

aka c.1341C>G (p.Ser447Arg or S447R) This mutation in the KCND2 gene is reported to be dominantly inherited and associated with early-onset (ages 22-50; mean 38) nocturnal paroxysmal atrial fibrillation, based on familial and functional studies.

C;G

see text and links via main rs-page

Source and license

Adapted from rs1011490341 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.