rs1044394

A SNP in the CHRNA4 gene on chromosome 20. Its most notable genotype is G;G: common in complete genomics

Gene
CHRNA4
Location
Chr 2063,350,733 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, AncestryDNA, FamilyTreeDNA
Minor allele frequency
13%

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in complete genomicsTypical · 0.070% of people
  2. A;AGoodcommon in clinvarTypical · 0.06% of people

SNPedia records rs1044394 on the minus strand: (C;C), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 10 HapMap populations.

  • AverageG;G 70% A;A 6%
  • European ancestry (Utah)G;G 90% A;A <1%
  • Han Chinese (Beijing)G;G 100% A;A 0%
  • Japanese (Tokyo)G;G 100% A;A 0%
  • Yoruba (Nigeria)G;G 32% A;A 22%
  • African ancestry (Southwest US)G;G 56% A;A 5%
  • Gujarati IndianG;G 90% A;A 0%
  • Luhya (Kenya)G;G 30% A;A 20%
  • Mexican ancestry (Los Angeles)G;G 85% A;A 0%
  • Maasai (Kenya)G;G 42% A;A 12%
  • TuscanG;G 79% A;A 1%

Other CHRNA4 SNPs

All CHRNA4 SNPs

Source and license

Adapted from rs1044394 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.