rs1045642(A;G)

Slower metaboliser for some drugs

Magnitude
2.0Worth knowing
Repute
Bad
Frequency
44%Average of 10 populations
On SNPedia
rs1045642(C;T)Minus strand
Gene
ABCB1

Frequency

Share of people with A;G in each HapMap population.

  • Mexican ancestry (Los Angeles)57%
  • European ancestry (Utah)56%
  • Chinese (Denver)56%
  • Japanese (Tokyo)53%
  • Gujarati Indian48%
  • Tuscan46%
  • Han Chinese (Beijing)45%
  • African ancestry (Southwest US)34%
  • Maasai (Kenya)26%
  • Yoruba (Nigeria)19%

Other genotypes of rs1045642

  1. G;GNot ratedincreased risk of cannabis dependence, lower (normal) cancer riskMinor · 1.041% of people
  2. A;AMost notableBadaltered drug metabolism and bioavailability; moderately increased risk for certain cancersImportant · 3.015% of people

All about rs1045642

Source and license

Adapted from rs1045642(C;T) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.