rs10468017
A SNP in the LOC101928635 gene on chromosome 15. Its most notable genotype is C;T: associated with higher HDL cholesterol
- Gene
- LOC101928635
- Location
- Chr 1558,386,313 (GRCh38)
- Highest magnitude
- 2.0Worth knowing
- Tested on
- 23andMe, AncestryDNA
- Minor allele frequency
- 21%
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;TMost notableGoodassociated with higher HDL cholesterol
- T;TGoodassociated with higher HDL cholesterol
On SNPedia: (C;T), (T;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Frequency
Share of each genotype in 11 HapMap populations.
- AverageC;T 29% T;T 4%
- European ancestry (Utah)C;T 53% T;T 5%
- Han Chinese (Beijing)C;T 28% T;T 5%
- Japanese (Tokyo)C;T 36% T;T 5%
- Yoruba (Nigeria)C;T 18% T;T 1%
- African ancestry (Southwest US)C;T 20% T;T 5%
- Chinese (Denver)C;T 23% T;T 3%
- Gujarati IndianC;T 31% T;T 6%
- Luhya (Kenya)C;T 16% T;T <1%
- Mexican ancestry (Los Angeles)C;T 28% T;T 2%
- Maasai (Kenya)C;T 29% T;T 3%
- TuscanC;T 36% T;T 6%
Related
Conditions, medicines and genes
Other LOC101928635 SNPs
- rs493258C;T1.15x risk of Age Related Macular DegenerationWorth knowing
- rs1800588C;Thigher HDL-C levelsMinor
- rs539901T;Tcommon genotypeTypical
- rs2414539A;Acommon in complete genomicsTypical
- rs4775041C;Clowest phosphatidylethanolamine valuesTypical
- rs16939881G;Gcommon genotypeTypical
- rs16940212G;Gcommon in complete genomicsTypical
Notes
From SNPedia
Notes
T allele is associated with 1.76mg/dl increase in HDL cholesterol (good cholesterol).
Source and license
Adapted from rs10468017 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.