rs104893666
A SNP in the SPR gene on chromosome 2. Its most notable genotype is C;T: Carrier of a SPR deficiency mutation
- Gene
- SPR
- Location
- Chr 272,888,497 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- AncestryDNA
Genotypes
As shown in 23andMe and AncestryDNA files.
- C;CGoodcommon in clinvar
- C;TMost notableBadCarrier of a SPR deficiency mutation
On SNPedia: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other SPR SNPs
- rs104893665A;GCarrier of a SPR deficiency mutationImportant
- rs121917746C;TCarrier of a SPR deficiency mutationImportant
- rs121917747A;TCarrier of a SPR deficiency mutationImportant
- rs387907200G;TCarrier of a SPR deficiency mutationImportant
- rs398122922A;GCarrier of a SPR deficiency mutationImportant
- rs587776777-;AGAACCarrier of a SPR deficiency mutationImportant
Notes
From SNPedia
Notes
aka c.488C>T (p.Pro163Leu)
C;T
Unaffected in absence of a second mutation in the SPR gene; see links via main rs-page.
Source and license
Adapted from rs104893666 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.