rs104893748

A SNP in the MYL3 gene on chromosome 3. Its most notable genotype is C;T: Familial Hypertrophic Cardiomyopathy

Gene
MYL3
Location
Chr 346,859,511 (GRCh38)
Highest magnitude
6.2Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TGoodcommon in clinvarTypical · 0.0
  2. C;TMost notableBadFamilial Hypertrophic CardiomyopathyVery important · 6.2

SNPedia records rs104893748 on the minus strand: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other MYL3 SNPs

All MYL3 SNPs

Notes

From SNPedia

Notes

Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle.

Source and license

Adapted from rs104893748 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.