rs104894073

A SNP in the GATA4 gene on chromosome 8. Its most notable genotype is A;G: Atrial septal defect, type 2

Gene
GATA4
Location
Chr 811,750,213 (GRCh38)
Highest magnitude
7.0Very important
Tested on
AncestryDNA

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. A;GMost notableBadAtrial septal defect, type 2Very important · 7.0
  2. G;GGoodcommon in clinvarTypical · 0.0

On SNPedia: (A;G), (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other GATA4 SNPs

All GATA4 SNPs

Notes

From SNPedia

Notes

rs104894073, also known as c.886G>A, p.Gly296Ser and G296S, represents a rare variant in the GATA4 gene. Inherited in an autosomal dominant manner, the rs104894073(A) allele is considered a causative mutation for atrial septal defect, type 2.

A;G

see discussion and links at rs104894073

Source and license

Adapted from rs104894073 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.