rs104894227

A SNP in the LRRC56 gene on chromosome 11. Its most notable genotype is C;T: Costello syndrome

Gene
LRRC56
Location
Chr 11533,553 (GRCh38)
Highest magnitude
7.0Very important
Tested on
AncestryDNA

Genotypes

Plus strand, as in 23andMe and AncestryDNA files.

  1. T;TGoodcommon in clinvarTypical · 0.0
  2. C;TMost notableBadCostello syndromeVery important · 7.0

SNPedia records rs104894227 on the minus strand: (A;A), (A;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Other LRRC56 SNPs

All LRRC56 SNPs

Notes

From SNPedia

Notes

aka c.350A>G (p.Lys117Arg) 23andMe name: i5005663

C;T

See links via main rs-page

Source and license

Adapted from rs104894227 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.