rs10489535

A SNP in the ACOT7 gene on chromosome 1. Its most notable genotype is G;G.

Gene
ACOT7
Location
Chr 16,283,765 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe
Minor allele frequency
6%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodNo summary available.Typical · 0.084% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 84%
  • European ancestry (Utah)G;G 94%
  • Han Chinese (Beijing)G;G 100%
  • Japanese (Tokyo)G;G 100%
  • Yoruba (Nigeria)G;G 58%
  • African ancestry (Southwest US)G;G 72%
  • Chinese (Denver)G;G 99%
  • Gujarati IndianG;G 91%
  • Luhya (Kenya)G;G 68%
  • Mexican ancestry (Los Angeles)G;G 95%
  • Maasai (Kenya)G;G 63%
  • TuscanG;G 89%

Conditions, medicines and genes

Notes

From SNPedia

Notes

rs10489535, a SNP in the ACOT7 gene, has been associated with both cholesterol levels and triglyceride levels in the Framingham Heart Study datasets, and is thus associated with heart disease. source

Source and license

Adapted from rs10489535 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.