rs1049353(C;C)

Likely better response to antidepressants if male

Magnitude
1.0Minor
Repute
Good
Frequency
81%Average of 10 populations
On SNPedia
rs1049353(G;G)Minus strand
Gene
CNR1

Frequency

Share of people with C;C in each HapMap population.

  • Maasai (Kenya)99%
  • Yoruba (Nigeria)97%
  • Chinese (Denver)87%
  • Japanese (Tokyo)86%
  • Han Chinese (Beijing)85%
  • Mexican ancestry (Los Angeles)83%
  • African ancestry (Southwest US)83%
  • Gujarati Indian65%
  • Tuscan64%
  • European ancestry (Utah)58%

Other genotypes of rs1049353

  1. T;TMost notableGoodLikely better response to antidepressants if femaleMinor · 1.02% of people
  2. C;TGoodless likely depressed in response to stressMinor · 1.018% of people

All about rs1049353

Notes

From SNPedia

the G allele may increase responsiveness to antidepressants but only in males.

Source and license

Adapted from rs1049353(G;G) on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.