rs10510468

A SNP in the PLCL2 gene on chromosome 3. Its most notable genotype is G;G: common in complete genomics

Gene
PLCL2
Location
Chr 316,897,125 (GRCh38)
Highest magnitude
0.0Typical
Tested on
23andMe, FamilyTreeDNA
Minor allele frequency
7%

Genotypes

As shown in 23andMe and AncestryDNA files.

  1. G;GMost notableGoodcommon in complete genomicsTypical · 0.084% of people

On SNPedia: (G;G). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.

Frequency

Share of each genotype in 11 HapMap populations.

  • AverageG;G 84%
  • European ancestry (Utah)G;G 94%
  • Han Chinese (Beijing)G;G 94%
  • Japanese (Tokyo)G;G 97%
  • Yoruba (Nigeria)G;G 62%
  • African ancestry (Southwest US)G;G 75%
  • Chinese (Denver)G;G 97%
  • Gujarati IndianG;G 88%
  • Luhya (Kenya)G;G 68%
  • Mexican ancestry (Los Angeles)G;G 79%
  • Maasai (Kenya)G;G 80%
  • TuscanG;G 93%

Conditions, medicines and genes

Notes

From SNPedia

Notes

SNP rs10510468 has been associated with both very-low density lipoprotein levels and high-density lipoprotein levels in the Framingham Heart Study datasets, and is thus associated with heart disease. source

Source and license

Adapted from rs10510468 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.

SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.