rs1057518183
A SNP in the SYNGAP1 gene on chromosome 6. Its most notable genotype is -;C: Mental retardation, type 5; SYNGAP1-related
- Gene
- SYNGAP1
- Location
- Chr 633,438,425 (GRCh38)
- Highest magnitude
- 8.8Very important
- Tested on
- Not on consumer chips
Genotypes
As shown in 23andMe and AncestryDNA files.
- -;CMost notableBadMental retardation, type 5; SYNGAP1-related
- C;CGoodcommon in clinvar
On SNPedia: (-;C), (C;C). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other SYNGAP1 SNPs
- rs121918315A;TMental retardation, type 5; SYNGAP1-relatedVery important
- rs121918316C;TMental retardation, type 5; SYNGAP1-relatedVery important
- rs397514670C;TMental retardation, type 5; SYNGAP1-relatedVery important
- rs397514741C;TMental retardation, type 5; SYNGAP1-relatedVery important
- rs397515320-;TMental retardation, type 5; SYNGAP1-relatedVery important
- rs587780470-;CMental retardation, type 5; SYNGAP1-relatedVery important
- rs587780474-;GMental retardation, type 5; SYNGAP1-relatedVery important
- rs797045012A;GMental retardation, type 5; SYNGAP1-relatedVery important
Notes
From SNPedia
Notes
-;C
SYNGAP1-related intellectual disability; see SYNGAP1 and links via rs-page
Source and license
Adapted from rs1057518183 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.