rs1057523837
A SNP in the SLC39A4 gene on chromosome 8. Its most notable genotype is A;G: Carrier of an acrodermatitis enteropathica mutation
- Gene
- SLC39A4
- Location
- Chr 8144,415,401 (GRCh38)
- Highest magnitude
- 3.0Important
- Tested on
- Not on consumer chips
Genotypes
Plus strand, as in 23andMe and AncestryDNA files.
- G;GGoodcommon in clinvar
- A;GMost notableBadCarrier of an acrodermatitis enteropathica mutation
SNPedia records rs1057523837 on the minus strand: (C;C), (C;T). Magnitude rates how notable a genotype is from 0 to 10, not how risky it is.
Related
Other SLC39A4 SNPs
- rs121434287A;GCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434288C;TCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434289C;TCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434290G;TCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434291C;TCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434292A;GCarrier of an acrodermatitis enteropathica mutationImportant
- rs121434293C;GCarrier of an acrodermatitis enteropathica mutationImportant
- rs782695425-;GCarrier of a likely acrodermatitis enteropathica mutationImportant
Notes
From SNPedia
Notes
aka c.493C>T (p.Gln165Ter) Reported by one ClinVar submitter as likely to be pathogenic, presumably for acrodermatitis enteropathica
A;G
Unaffected in absence of a second SLC39A4 mutation; see links via main rs-page for more information.
Source and license
Adapted from rs1057523837 on SNPedia, using a snapshot taken October 16, 2026. SNPedia content is shared under CC BY-NC-SA 3.0 US, and this page is shared under the same license.
SNPedia is a community-edited wiki. Its entries can be incomplete, out of date or wrong, and nothing here is a diagnosis or medical advice. Magnitude is a community rating of how interesting a genotype is, not a risk score.